|
Size: 1104
Comment:
|
Size: 1552
Comment:
|
| Deletions are marked like this. | Additions are marked like this. |
| Line 2: | Line 2: |
| see https://surfer.nmr.mgh.harvard.edu/fswiki/CorticalParcellation_Yeo2011 for example | |
| Line 4: | Line 3: |
| intro here, | {{attachment:flateconlyinflated2014.jpg}} |
| Line 6: | Line 5: |
| be sure to discuss the difference between the ec label thats included in the aparc atlas versus this new ec label. | ''Author: Jean Augustinack'' The entorhinal cortex is located on the crown of the anterior parahippocampal gyrus. Brodmann assigned the number 28 to entorhinal cortex (Brodmann’s area 28). Entorhinal cortex displays a unique cytoarchitecture with large neurons in layer II that form clusters. The entorhinal cortex is the gateway to the hippocampus. In Alzheimer’s disease (AD), neurons in the entorhinal cortex, particularly those in layer II, begin to die and some leave behind a pathological marker – the neurofibrillary tangle. Neurofibrillary tangles and significant cell death characterize the neuronal loss in AD where neurofibrillary tangles and subsequent atrophy have been correlated with dementia. |
| Line 10: | Line 11: |
| == Parcellations in FreeSurfer Surface Space == ||'''7 Network Estimate''' || || {{attachment:Yeo2011_JNeurophysiol_7networks_lateral.png}} || || {{attachment:Yeo2011_JNeurophysiol_7networks_medial.png}} || |
Please note that there two entorhinal labels exist in FreeSurfer 1) the EC label included in the aparc atlas and 2) the cytoarchitecturally-defined entorhinal label (i.e., the ex vivo one). |
| Line 16: | Line 14: |
| you have three options for using these labels: | Reference for Entorhinal cortex, Cytoarchitecturally-defined labels: |
| Line 18: | Line 16: |
| labels in freesurfer surface space are in subjects dir subj/label/?h.perirhinal.label | Fischl B, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 1;47(1):8-17. |
| Line 20: | Line 18: |
| instructions on how to view in freeview | == Where to find the entorhinal (cytoarchitectural-defined) labels in FreeSurfer == |
| Line 22: | Line 21: |
| where to get stats on this label (../stats/$hemi.BA.stats) | Right and left labels for entorhinal are available in freesurfer 5.3 |
| Line 24: | Line 23: |
| already in freesurfer 5.3 | The labels are in freesurfer surface space and located in subjects dir subj/label/?h.entorhinal_exvivo.label |
| Line 26: | Line 25: |
| label in volume space | See instructions on how to view in freeview |
| Line 28: | Line 27: |
| mapping surface label to subjects volume space will be available in v6 or if you have freesurfer, run this to map from surface space to volume space and then this is how you view it. label in fsaverage volume space [[attachment:perirhinal_fsaverage.nii]] label in mni152 volume space [[attachment:perirhinal_mni152.nii]] |
To generate stats on this label (../stats/$hemi.BA.stats) |
Entorhinal Cortex
Author: Jean Augustinack
The entorhinal cortex is located on the crown of the anterior parahippocampal gyrus. Brodmann assigned the number 28 to entorhinal cortex (Brodmann’s area 28). Entorhinal cortex displays a unique cytoarchitecture with large neurons in layer II that form clusters. The entorhinal cortex is the gateway to the hippocampus. In Alzheimer’s disease (AD), neurons in the entorhinal cortex, particularly those in layer II, begin to die and some leave behind a pathological marker – the neurofibrillary tangle. Neurofibrillary tangles and significant cell death characterize the neuronal loss in AD where neurofibrillary tangles and subsequent atrophy have been correlated with dementia.
Please note that there two entorhinal labels exist in FreeSurfer 1) the EC label included in the aparc atlas and 2) the cytoarchitecturally-defined entorhinal label (i.e., the ex vivo one).
Reference for Entorhinal cortex, Cytoarchitecturally-defined labels:
Fischl B, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 1;47(1):8-17.
Where to find the entorhinal (cytoarchitectural-defined) labels in FreeSurfer
Right and left labels for entorhinal are available in freesurfer 5.3
The labels are in freesurfer surface space and located in subjects dir subj/label/?h.entorhinal_exvivo.label
See instructions on how to view in freeview
To generate stats on this label (../stats/$hemi.BA.stats)
