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| = THIS PAGE HAS BEEN MOVED TO SHAREPOINT! = Please refer to this site/make edits here for the most updated information: https://partnershealthcare.sharepoint.com/sites/LCN/SitePages/Entorhinal.aspx ---- <<BR>> <<BR>> <<BR>> |
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| see https://surfer.nmr.mgh.harvard.edu/fswiki/CorticalParcellation_Yeo2011 for example | |
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| intro here, | {{attachment:flateconlyinflated2014.jpg}} |
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| be sure to discuss the difference between the ec label thats included in the aparc atlas versus this new ec label. | ''Author: Jean Augustinack'' |
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| The entorhinal cortex is located on the crown of the anterior parahippocampal gyrus. Brodmann assigned the number 28 to entorhinal cortex (Brodmann’s area 28). Entorhinal cortex displays a unique cytoarchitecture with large neurons in layer II that form clusters. The entorhinal cortex is the gateway to the hippocampus. In Alzheimer’s disease (AD), neurons in the entorhinal cortex, particularly those in layer II, begin to die and some leave behind a pathological marker – the neurofibrillary tangle. Neurofibrillary tangles and significant cell death characterize the neuronal loss in AD where neurofibrillary tangles and subsequent atrophy have been correlated with dementia. | |
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| Please note that there two entorhinal labels exist in FreeSurfer 1) the EC label included in the aparc atlas and 2) the cytoarchitecturally-defined entorhinal label (i.e., the ex vivo one). | |
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| == Parcellations in FreeSurfer Surface Space == ||'''7 Network Estimate''' || || {{attachment:Yeo2011_JNeurophysiol_7networks_lateral.png}} || || {{attachment:Yeo2011_JNeurophysiol_7networks_medial.png}} || |
Reference for Entorhinal cortex, Cytoarchitecturally-defined labels: |
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| Fischl B, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 1;47(1):8-17. | |
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| you have three options for using these labels: | == Where to find the entorhinal (cytoarchitectural-defined) labels in FreeSurfer == |
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| labels in freesurfer surface space are in subjects dir subj/label/?h.perirhinal.label | Right and left labels for entorhinal are available in freesurfer 5.3 and 6.0+. |
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| instructions on how to view in freeview | The labels are in freesurfer surface space and located in subjects dir: {{{ subj/label/?h.entorhinal_exvivo.label }}} |
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| where to get stats on this label (../stats/$hemi.BA.stats) | They are generated by default by: {{{ recon-all -all }}} but can be regenerated with: {{{ recon-all -ba-labels }}} |
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| already in freesurfer 5.3 | In freeview, after loading a surface, the label can be viewed either by loading the Annotation file: {{{ subj/label/?h.BA_exvivo.annot }}} or by loading the Label file: {{{ subj/label/?h.entorhinal_exvivo.label }}} (which allows selection of 'Heat Scale' viewing mode to display the probability mapping), or by loading the Label file: {{{ subj/label/?h.entorhinal_exvivo.thresh.label }}} which is a thresholded version, more suitable as an ROI. |
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| label in volume space | Stats on this label are found in: {{{ subj/stats/?h.BA_exvivo.stats }}} |
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| mapping surface label to subjects volume space will be available in v6 or if you have freesurfer, run this to map from surface space to volume space and then this is how you view it. label in fsaverage volume space [[attachment:perirhinal_fsaverage.nii]] label in mni152 volume space [[attachment:perirhinal_mni152.nii]] |
See also: * [[BrodmannAreaMaps]] * [[Perirhinal]] * [[ExVivoEcPcLabelsFsaverage]] |
THIS PAGE HAS BEEN MOVED TO SHAREPOINT!
Please refer to this site/make edits here for the most updated information: https://partnershealthcare.sharepoint.com/sites/LCN/SitePages/Entorhinal.aspx
Entorhinal Cortex
Author: Jean Augustinack
The entorhinal cortex is located on the crown of the anterior parahippocampal gyrus. Brodmann assigned the number 28 to entorhinal cortex (Brodmann’s area 28). Entorhinal cortex displays a unique cytoarchitecture with large neurons in layer II that form clusters. The entorhinal cortex is the gateway to the hippocampus. In Alzheimer’s disease (AD), neurons in the entorhinal cortex, particularly those in layer II, begin to die and some leave behind a pathological marker – the neurofibrillary tangle. Neurofibrillary tangles and significant cell death characterize the neuronal loss in AD where neurofibrillary tangles and subsequent atrophy have been correlated with dementia.
Please note that there two entorhinal labels exist in FreeSurfer 1) the EC label included in the aparc atlas and 2) the cytoarchitecturally-defined entorhinal label (i.e., the ex vivo one).
Reference for Entorhinal cortex, Cytoarchitecturally-defined labels:
Fischl B, et al. Predicting the location of entorhinal cortex from MRI. Neuroimage. 2009 Aug 1;47(1):8-17.
Where to find the entorhinal (cytoarchitectural-defined) labels in FreeSurfer
Right and left labels for entorhinal are available in freesurfer 5.3 and 6.0+.
The labels are in freesurfer surface space and located in subjects dir:
subj/label/?h.entorhinal_exvivo.label
They are generated by default by:
recon-all -all
but can be regenerated with:
recon-all -ba-labels
In freeview, after loading a surface, the label can be viewed either by loading the Annotation file:
subj/label/?h.BA_exvivo.annot
or by loading the Label file:
subj/label/?h.entorhinal_exvivo.label
(which allows selection of 'Heat Scale' viewing mode to display the probability mapping), or by loading the Label file:
subj/label/?h.entorhinal_exvivo.thresh.label
which is a thresholded version, more suitable as an ROI.
Stats on this label are found in:
subj/stats/?h.BA_exvivo.stats
See also: