PETSurfer provides a set of tools within FreeSurfer for Partical Volume Correction (PVC) and Kinetic Modeling. While these are typically used for PET analysis, the tools can be used in any context where PVC is needed. PVC methods include the Symmetric Geometric Transfer Matrix (SGTM), two-compartment model (also known as the Meltzer Method), three-compartment model (also known as the Muller-Gartner Method), region-based voxel-wise (RBV). PVC also accounts for the volume fraction effect. PETSurfer will be released with FreeSurfer version 6.
1. gtmseg --s subject
where "subject" is the name of the FreeSurfer subject when you ran recon-all. This creates several files in the FS folder used to run the PVC methods. This should take about an hour or two.
1. Register your PET image with the anatomical: