Index
Contents
Name
mri_ms_fitparms - Estimates tissue parameter maps (T1, proton density) from multi-spectral FLASH MRI
Synopsis
mri_ms_fitparms [options] <volume1> <volume2> ... <output directory>
Arguments
Positional Arguments
| volume1 | 3D FLASH flip angle1 | Volume must be in mgh format | 
| volume2 | 3D FLASH flip angle2 | Volume must be in mgh format | 
| output directory | Where T1 and PD maps are written | 
Required Flagged Arguments
None
Optional Flagged Arguments
| -afi, -fam | Designate flip angle map, we assume that the nominal flip angle is 60 degrees if B1 was homogeneous <also assumes that the afi map is registered to the flash volumes> | 
| -ait | Apply inverse of transform | 
| -at | Set acquisition time | 
| -conform | Interpolate volume to be isotropic 1mm^3 | 
| -correct | Correct proton density map (PD) by T2* estimates | 
| -cubic | Use cubic interpolation | 
| -dt | Numerical integration time step used to estimate the flip angle field from multiple acquisitions of different flip angles and/or TRs | 
| -fa | Flip angle (degrees) | 
| -fa_scale | Set value to scale all flip angles by | 
| -faf | Designate flip angle map to use with specified control points | 
| -fsmooth | Smooth flip angle map for X iterations of soap bubble smoothing (thres=??) | 
| -i | Invert | 
| -m | Set momentum | 
| -max | Set max T2* | 
| -n | Perform estimation/motion correction X times (-n 0 runs without motion correction) | 
| -nearest | Use nearest-neighbor interpolation | 
| -nocompress | Do not compress output volumes (save as .mgh) | 
| -nosynth | Disable volume synthesis | 
| -r | write out residuals to designated location | 
| -s | Smooth faf field with sigma=X | 
| -scale | Scale volumes by X after reading | 
| -sinc | Use sinc interpolation (default window width is 6) | 
| -t | Apply transform to output volumes | 
| -te | Echo time (ms) | 
| -tr | Repetition time (ms) | 
| -trilinear | Use trilinear interpolation | 
| -tukey | Use tukey bi-weight of residuals | 
| -u | ??? | 
| -use_brain_mask | Compute a brain mask from the PD map and use it when computing registration | 
| -w | Write out intermediate results every X iterations | 
| -window | ??? | 
Outputs
| T1.mgz | Compressed T1 map | 
| PD.mgz | Compressed Proton Density map | 
| vol0.mgz | Compressed Synthetic volume for input <volume1>, in motion corrected space | 
| vol0.lta | Motion correction afine information (text file) | 
| vol1.mgz | Compressed Synthetic volume for input <volume2>, in motion corrected space | 
| vol1.lta | Motion correction afine information (text file) | 
Description
This program takes an arbitrary # of FLASH images as input, and estimates the T1 and PD values of the data for voxel, as well as a linear transform aligning each of the images. The T1 and PD maps are written into <output directory> together with synthetic volumes names vol?.mgh, one for each of the input volumes. All the output volumes are generated in the common (motion-corrected) space. Note that TR, TE and the flip angle are read directly from the image header. If this information is not available, it can be specified on the command line using -tr <TR in msec> -te <TE in msec> -fa <flip angle in degrees> before each volume.
Examples
Example 1
cd subjectid/mri/flash
mri_ms_fitparms -tr 20 -te 6 -fa 5 flash5.mgh -tr 20 -te 6 -fa 30 flash30.mgh .
Description: Two 3D FLASH volumes (flip angles 5 and 30 degrees), both acquired with the same TE (20ms) and TR (6ms) are used to fit T1 and PD map and write the results on the same directory (subjectid/mri/flash).
Bugs
None
See Also
| (to convert input volumes to mgh format) | 
 | |
| (to use the T1 and PD maps to create synthetic images) | 
 | 
Links
Methods Description
N/A
References
None
Reporting Bugs
Report bugs to < analysis-bugs@nmr.mgh.harvard.edu >